Acetylation of N-acetylneuraminic acid and its methyl ester
✍ Scribed by Alberto Marra; Pierre Sinay
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- English
- Weight
- 429 KB
- Volume
- 190
- Category
- Article
- ISSN
- 0008-6215
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📜 SIMILAR VOLUMES
Hudson and A. Kunz, J. Am. Chem. Ss., 47, 2052 (1925) . 12. Treatment at a lower temperature (-15 "C) rc>sulted 1~. a lo:qer-)rleld (23%). 13. T. Ogawa ant! 11. Silglmoto, Carbohydcl\_.\_ Kc-., 135, c5-C9 (1985); ar:d ti1c references cited therein.
## Abstract Two new fluorescent regioselective __O__‐acetylated __N__‐acetylneuraminic acid (Neu5Ac) thioketosides, 2α‐[4‐(dansylamino)phenylthio]‐7,8,9‐tri‐__O__‐acetyl‐__N__‐acetylneuraminic acid {2α‐[4‐(dansylamino)phenylthio]‐Neu5,7,8,9Ac~4~} (3) and 2α‐[4‐(dansylamino)phenylthio]‐4‐__O__‐acety
A synthesis of N-acetylneuraminic acid (1) and of N-acetyl-4-epineuraminic acid (2, R = H) from 2-acetamido-4,6-O-benzylidene-l,2-dideoxy-1 -nitro-D-mannopyranose (3) and 2-acetamido-l,2-dideoxy-4,6-0-isopropylidene-l -nitro-D-mannopyranose (4), respectively, is described. Michael addition of 3 and
Sialic acids are involved in numerous biological processes, including cell-cell recognition, cell differentiation, and viral infection'. They are principally found in plasma membranes of animal cells at the non-reducing terminus of the carbohydrate moieties of glycoproteins and glycolipids, where th
## Abstract __N__‐acetyl‐4‐nitrotryptophan methyl ester (2), __N__‐acetyl‐5‐nitrotryptophan methyl ester (3), __N__‐acetyl‐6‐nitrotryptophan methyl ester (4) and __N__‐acetyl‐7‐nitrotryptophan methyl ester (5) were synthesized through a modified malonic ester reaction of the appropriate nitrogramin