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Acetylation and trifluoroacetylation reactions of tetrahydropyrrolo[3,2-c]pyridines

✍ Scribed by Tatiana N. Borisova; Leonid G. Voskressensky; Tatiana A. Soklakova; Bonifas Nsabimana; Alexey V. Varlamov

Book ID
119768000
Publisher
Royal Society of Chemistry
Year
2002
Tongue
English
Weight
85 KB
Volume
12
Category
Article
ISSN
0959-9436

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It has been shown that the most efficient catalysts for the synthesis of 4,5, 7-trimethyl-4,5,6, 7tetrahydropyrrolo[3,2-c]pyridine from 1,2,5-trimethylpyridin-4-one and acetylene under Trofimov conditions are rubidium and potassium hydroxides. Use of Triton B or a mixture of trimethylbenzylammonium