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Acetyl-L-carnitine-mediated neuroprotection during hypoxia is attributed to ERK1/2-Nrf2-regulated mitochondrial biosynthesis

โœ Scribed by Kalpana Barhwal Hota; Sunil Kumar Hota; Om Prakash Chaurasia; Shashi Bala Singh


Book ID
102854029
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
903 KB
Volume
22
Category
Article
ISSN
1050-9631

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## Abstract Cellular and molecular pathways underlying hypoxic neurotoxicity and cell death are multifaceted and complex. Although many potentially neuroprotective agents have been investigated, the protection conferred is often inadequate, resulting in their insufficient clinical utility. In light