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Acetyl-CoA—Life at the metabolic nexus

✍ Scribed by David J. Oliver; Basil J. Nikolau; Eve Syrkin Wurtele

Book ID
116837709
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
466 KB
Volume
176
Category
Article
ISSN
0168-9452

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## Abstract Breast cancer‐associated mutations affecting the highly‐conserved C‐terminal BRCT domains of the tumor suppressor gene __br__east __ca__ncer susceptibility gene __1__ (BRCA1) fully disrupt the ability of BRCA1 to interact with __a__cetyl __c__oenzyme A __c__arboxylase __a__lpha (ACCA),