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Acetaminophen‐Induced Hepatotoxicity: Role of Metabolic Activation, Reactive Oxygen/Nitrogen Species, and Mitochondrial Permeability Transition

✍ Scribed by Hinson, Jack A.; Reid, Angela B.; McCullough, Sandra S.; James, Laura P.

Book ID: 118245556
Publisher: Informa plc
Year: 2004
Tongue: English
Weight: 225 KB
Volume: 36
Category: Article
ISSN: 0360-2532
DOI: 10.1081/dmr-200033494

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## Abstract Screening of various natural products in a search for novel inducers of apoptosis in human leukemia cells led us to identify the strong apoptosis‐inducing activity in a fraction extracted with methanol from the roots of __Sophora subprostrata__ Chun et T. Chen. We purified the compound