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Acetaldehyde, but not ethanol, induces sister chromatid exchanges in chinese hamster cells in vitro

✍ Scribed by G. Obe; H. Ristow

Book ID
113191222
Publisher
Elsevier Science
Year
1977
Tongue
English
Weight
209 KB
Volume
56
Category
Article
ISSN
0027-5107

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Glutathione (GSH) dissolved in Eagle's MEM and added to cultures of V79-E cells in concentrations between 2.5 X 10 -4 and 10 -3 moles/l for 1 h induces a dose-dependent cell cycle delay, sister chromatid exchanges and clastogenic damage. 7-8% of the metaphases showed endoreduplication at a recovery