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Acetaldehyde activates Jun/AP-1 expression and DNA binding activity in human oral keratinocytes

✍ Scribed by Sherry R Timmons; Joseph O Nwankwo; Frederick E Domann

Book ID: 114393804
Publisher: Elsevier Science
Year: 2002
Tongue: English
Weight: 232 KB
Volume: 38
Category: Article
ISSN: 1368-8375
DOI: 10.1016/s1368-8375(01)00056-2

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## Abstract Transcription factor activator protein‐1 (AP‐1) super‐family is known to modulate expression of array of genes during development of many cancers and considered as an important target for modern therapeutics. But the role of AP‐1 during development of human oral cancers is still poorly