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Accurate Translation of the Genetic Code Depends on tRNA Modified Nucleosides

✍ Scribed by Yarian, C.


Book ID
111931023
Publisher
The American Society for Biochemistry and Molecular Biology
Year
2002
Tongue
English
Weight
201 KB
Volume
277
Category
Article
ISSN
0021-9258

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Modified nucleoside-dependent transition
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Biologically active DNA analogs of tRNA Phe (tDNA phi) were used to investigate metal ion interaction with tRNA-like structures lacking the 2'OH. Binding of Mg 2 Β§ to the 76 oligonucleotide tDNA ehe, monitored by circular dichroism spectroscopy, increased base stacking and thus the conformational st