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Accurate determination of low pK values by 1H NMR titration

✍ Scribed by Zoltán Szakács; Gerhard Hägele

Book ID
116900342
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
131 KB
Volume
62
Category
Article
ISSN
0039-9140

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We demonstrate the application of the proton inverse detected deuteron (PRIDE) NMR technique to the measurement of the orientation of membrane-bound peptides with enhanced sensitivity. Gramicidin D, a transmembrane peptide, and ovispirin, a surfacebound peptide, were used as model systems. The pepti