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Accuracy of an array comparative genomic hybridization (CGH) technique in detecting DNA copy number aberrations: comparison with conventional CGH and loss of heterozygosity analysis in prostate cancer

✍ Scribed by Seiji Yano; Hideyasu Matsuyama; Kenji Matsuda; Hiroaki Matsumoto; Satoru Yoshihiro; Katsusuke Naito

Book ID
113512328
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
253 KB
Volume
150
Category
Article
ISSN
0165-4608

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## Abstract We have undertaken an extensive high‐resolution analysis of loss of heterozygosity (LOH) in 30 high grade gliomas using the Affymetrix 100K SNP mapping array. Only 70% of LOH events were accompanied by a copy number loss (CNA~loss~), and of the other 30%, the distal region of 17p prefer