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Accumulation of Triglycerides in Liver following Inhibition of Fatty Acid Oxidation by 3-Mercaptopropionic Acid in Perfused Liver

✍ Scribed by MUNEHIKO YAMAMOTO; YASUHIRO NAKAMURA; IWAHIKO YAMAMOTO; ISOKO TAKAZONO

Book ID
119869041
Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
137 KB
Volume
683
Category
Article
ISSN
0890-6564

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Diltiazem inhibits fatty acid oxidation
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The eects of diltiazem on fatty acid metabolism were measured in the isolated perfused rat liver and in isolated mitochondria. In the perfused rat liver diltiazem inhibited oxygen uptake and ketogenesis from endogenous substrates. Ketogenesis from exogenously supplied palmitate was also inhibited. T