The activity of 3-hydroxy-3-methylglutar
✍
Harry W. Chen
📂
Article
📅
1981
🏛
John Wiley and Sons
🌐
English
⚖ 577 KB
## Abstract The specific activity of HMG‐CoA reductase, the major rate‐limiting enzyme in the sterol biosynthetic pathway, declined linearly with increasing cell density in four different lines of mammalian cell cultures. As expected, this caused the rates of sterol synthesis from [^14^C]acetate to