Genetics of the malignant progression of
โ
Tom Mikkelsen; J. Gregory Cairncross; Webster K. Cavenee
๐
Article
๐
1991
๐
John Wiley and Sons
๐
English
โ 570 KB
The tendency of human cancers to progress towards a more malignant state over time is a well described biological phenomenon. Recent investigations elucidating the genetic nature of malignancy and the possible mechanisms responsible for this evolution have suggested that a sequential pathway may exi