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Accumulation of autoreactive effector T cells and allo-specific regulatory T cells in the pancreas allograft of a type 1 diabetic recipient

✍ Scribed by J. H. Velthuis; W. W. Unger; A. R. van der Slik; G. Duinkerken; M. Engelse; A. F. Schaapherder; J. Ringers; C. van Kooten; E. J. de Koning; B. O. Roep


Publisher
Springer
Year
2008
Tongue
English
Weight
358 KB
Volume
52
Category
Article
ISSN
0012-186X

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## Abstract Treg can suppress autoimmune diseases such as type 1 diabetes, but their __in vivo__ activity during suppression remains poorly characterized. In type 1 diabetes, Treg activity has been demonstrated in the pancreatic lymph node, but little has been studied in the pancreas, the site of a