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Accumulation of amyloid β protein in Tg2576 mice

✍ Scribed by Takeshi Kawarabayashi; Tetsuro Murakami; Etsuro Matsubara; Mikio Shoji; Koji Abe

Book ID
117550983
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
61 KB
Volume
1252
Category
Article
ISSN
0531-5131

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## Abstract We measured tissue distribution and expression pattern of the beta‐site amyloid precursor protein (APP)‐cleaving enzyme (BACE) in the brains of transgenic Tg2576 mice that show amyloid pathology. BACE protein was expressed at high levels in brain; at lower levels in heart and liver; and