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Accumulation of 5-Aminolevulinic Acid-Induced Protoporphyrin IX in Normal and Neoplastic Human Endometrial Epithelial Cells

✍ Scribed by M.T. Wyss-Desserich; C.H. Sun; P. Wyss; C.S. Kurlawalla; U. Haller; M.W. Berns; Y. Tadir

Book ID
115578778
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
111 KB
Volume
224
Category
Article
ISSN
0006-291X

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Protoporphyrin IX (Pp IX) is the main photosensitizer in photochemotherapy with 5-aminolevulinic acid (ALA). Pp IX is photolabile and the present work shows that 70-95% of Pp IX in cells is degraded by clinically relevant light exposures (40-200 J cm 22 at 630 nm). During light exposure a small yiel