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Accumulation and expression of serum amyloid P component in human atherosclerotic lesions

✍ Scribed by Zhiqing Song; Lei Cai; Ling Guo; Yoshitane Tsukamoto; Chikao Yutani; Xiang-An Li


Book ID
118422964
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
532 KB
Volume
211
Category
Article
ISSN
0021-9150

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To analyze the regulation of human serum amyloid P component (SAP) gene expression, we have produced seven transgenic mice. The 3.3 kb human SAP genes containing about 0.8 kb of 5' and 1.5 kb of 3' flanking region were injected into fertilized eggs of C57BL/6 mice. In five of the seven transgenic mi