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Accessibility of the S4 Arginines in the Human Voltage Gated Proton Channel, hHV1

✍ Scribed by Musset, Boris; Smith, Susan M.E.; Kulleperuma, Kethica; Morgan, Deri; Holyoake, John; Chakrabarti, Nilmadhab; Cherny, Vladimir V.; Pomès, Régis; DeCoursey, Thomas E.

Book ID
120901846
Publisher
Biophysical Society
Year
2013
Tongue
English
Weight
45 KB
Volume
104
Category
Article
ISSN
0006-3495

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A possible role for phosphate in complex
A possible role for phosphate in complexing the arginines of S4 in voltage gated channels
✍ Michael E. Green 📂 Article 📅 2005 🏛 Elsevier Science 🌐 English ⚖ 286 KB

Phosphate ions are known to complex guanidinium groups, which are the side chains of arginine. Voltage gated channels that allow passage of ions through cell membranes, producing, for example the nerve impulse, are in many cases composed of four domains, each with six transmembrane segments. The S4