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Acceptance of chorionic villus sampling in the southwest region of the Netherlands: A 5-Year evaluation

✍ Scribed by Brandenburg, H. ;Jahoda, M. G. J. ;Los, F. J. ;Wladimiroff, J. W.

Publisher: John Wiley and Sons
Year: 1991
Tongue: English
Weight: 245 KB
Volume: 41
Category: Article
ISSN: 0148-7299
DOI: 10.1002/ajmg.1320410221

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✦ Synopsis

Abstract

The acceptance of chorionic villus sampling (CVS) for monitoring pregnancies at risk for chromosomal and genetic disorders was studied from its introduction in the Centre for Clinical Genetics in Rotterdam in 1984 until 1988. Special attention was given to increasing acceptance in the group with advanced maternal age (AMA) (12.6% CVS in 1984, 52.2% CVS in 1988) and the group with a high genetic risk (HGR) (42.7% in 1984, 86.7% in 1988). The odds‐growth‐rate in CVS was 1.64 and 1.67 respectively, which was not significantly different. The relatively limited use of CVS at AMA is most likely determined by the fact that a considerable number of patients are referred too late in pregnancy to have the option of CVS.

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