Acceleration of in vitro dissolution studies of sustained release dosage form of theophylline and in vitro–in vivo evaluations in terms of correlations
✍ Scribed by Gökhan Ertan; Ercüment Karasulu; Işık Özgüney; Yeşim Karasulu; Şebnem Apaydın; Gülten Kantarcı; Aysu Yurdasiper; Mehmet Ali Ege
- Book ID
- 107697996
- Publisher
- Springer-Verlag
- Year
- 2011
- Tongue
- English
- Weight
- 375 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0378-7966
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Six preparations were considered: three multiple unit dosage forms (micropellets in capsules) (D, E and G) and one matrix tablet (B) were experimental prolonged release formulations, two non-disintegrating tablets (A and C) were commercial products. The in vitro dissolution behaviour of the differin
The object of the study was to develop an oral dosage form of aminorex which would produce prolonged, stable plasma levels of total drug. Since no definite set of dissolution conditions exists for the evaluation of the in uiuo availability of a given drug, an arbitrary set of dissolution conditions