Acceleration Effect of Human Recombinant Bone Morphogenetic Protein-2 on Differentiation of Human Pulp Cells Into Odontoblasts
β Scribed by Takashi Saito; Masafumi Ogawa; Yoshiaki Hata; Kazuhisa Bessho
- Book ID
- 117855923
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 314 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0099-2399
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Bone morphogenetic proteins (BMPs) are factors that promote osteoblastic cell differentiation and osteogenesis. It is unknown whether BMPs may act on human osteoblastic cells by increasing immature cell growth and/or differentiation. We investigated the short- and long-term effects of recombinant hu
Recombinant human bone morphogenetic protein-2 (rhBMP-2) is known to induce orthotopic and ectopic bone formation in vivo. Several in vitro studies using rat or mouse clonal cell lines have shown that rhBMP-2 may be involved in the differentiation of osteoblasts from osteoblast precursor cells or st