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Accelerated evolution in the reactive centre regions of serine protease inhibitors

✍ Scribed by Hill, Robert E.; Hastie, Nicholas D.

Book ID
109748615
Publisher
Nature Publishing Group
Year
1987
Tongue
English
Weight
461 KB
Volume
326
Category
Article
ISSN
0028-0836

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πŸ“œ SIMILAR VOLUMES

Cartilage synthesizes the serine proteas
Cartilage synthesizes the serine protease inhibitor PAI-1: Support for the involvement of serine proteases in cartilage remodeling
✍ Dr. Benjamin V. Treadwell; Michele Pavia; Christine A. Towle; Vernon J. Cooley; πŸ“‚ Article πŸ“… 1991 πŸ› Elsevier Science 🌐 English βš– 763 KB

## Abstract The work described here demonstrates the synthesis by human articular cartilage of plasminogen activator inhibitor‐1 (PAI‐1), a potent inhibitor of the serine protease tissue plasminogen activator (tPA). We also present data demonstrating an increase in PAI‐1 messenger ribonucleic acid