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Acanthosis Nigricans and the sign of leser-trélat associated with adenocarcinoma of the gallbladder

✍ Scribed by Michael I. Jacobs; Darrell S. Rigel


Publisher
John Wiley and Sons
Year
1981
Tongue
English
Weight
530 KB
Volume
48
Category
Article
ISSN
0008-543X

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✦ Synopsis


A case of adenocarcinoma of the gallbladder associated with acanthosis nigricans and the sign of Leser-Trelat is presented. The significant underrepresentation of adenocarcinoma of the gallbladder in association with malignant acanthosis nigricans is noted. If malignant acanthosis nigricans is caused by an ectopic peptide, a relative lack of production of the postulated substance by gallbladder adenocarcinoma cells could account for this finding.


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