Poster Session Abstracts: Abstracts 1β68
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Article
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1998
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John Wiley and Sons
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English
β 292 KB
The vast majority of cases of cystic Γbrosis are the result of a single amino acid deletion (DF508) in the sequence of CFTR. The result of this deletion is that the DF-CFTR misfolds and does not obtain its normal residence in the plasma membrane of cells, but instead is proteolyzed. The F508-contain