Abstract of a polysaccharide related to the blood group substances and its reaction with borate. I. A study by electrophoresis: Laura E. Krejci, Lucile Sweeny, and Charles A. Zittle (Arch. Biochem., 22:253, 1949)

• Publisher: Elsevier Science
• Year: 1950
• Tongue: English
• Weight: 74 KB
• Volume: 249
• Category: Article
• ISSN: 0016-0032
• DOI: 10.1016/s0016-0032(50)91110-0

✦ Synopsis

of A Polysaccharide Related to the Blood Group Substances and its Reaction with Borate. I. A Study by Electrophoresis.--LAURA E. KREJCI, LUCILE SWEENY, AND CHARLES A. ZITTLE (Arch. Biochem., 22:253, 1949). A polysaccharide isolated from calf intestinal mucosa, and related serologically to the blood group A and B substances, exhibits increased mobility in the presence of borate ions through formation of diol-borate compounds of increased acidity. The mobility increments were found to vary with (1) pH, (2) borate ion concentration, and (3) polysaccharide concentration. Together, (2) and (3) determine the concentrations of the diol-borate compounds, and (1) determines" the degree of ionization of those compounds. A sharpening of the electrophoresis boundaries paralleled the rise in mobility.