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Absorption kinetics of cyclosporine in healthy volunteers

✍ Scribed by Suneel K. Gupta; Leslie Z. Benet

Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
265 KB
Volume
10
Category
Article
ISSN
0142-2782

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✦ Synopsis

The absorption kinetics of cyclosporine were studied in eight healthy volunteers following oral and intravenous administration. Bioavailability of cyclosporine was observed to be 20.8 + 5.5 per cent. Absorption of cyclosporine was found to be better described by first order processes rather than by a zero order process as previously reported.

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