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Absorption, Excretion and Urinary Metabolic Pattern of 3 H-Albuterol Aerosol in Man

✍ Scribed by Lin, C.; Magat, J.; Calesnick, B.; Symchowicz, S.


Book ID
126693914
Publisher
Informa plc
Year
1972
Tongue
English
Weight
468 KB
Volume
2
Category
Article
ISSN
0049-8254

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35S-Furosemide was administered to beagle dogs and rhesus monkeys in an oral solution on a single and a 20 repeated 5-mg/kg/day dosing regimen. Following the single dose, 25.0% (dogs) and 24.0% (monkeys) of the dose were excreted in the urine in 24 hr. TLC analysis demonstrated that both species had