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Absorption and distribution of oxafuradene in the dog

โœ Scribed by John D. Conklin; James A. Buzard

Publisher
John Wiley and Sons
Year
1965
Tongue
English
Weight
468 KB
Volume
54
Category
Article
ISSN
0022-3549

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The percutaneous absorption and disposition of iodochlorhydroxyquin (5-chloro-7-iodo-8-quinolinol; I) from a 3% cream were studied in five dogs over a 28-d topical treatment period. Plasma levels, determined by HPLC, were 0.275-0.525 microgram/mL. The steady-state elimination rate of total I in urin