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Absolute configuration of norzoanthamine, a promising candidate for an osteoporotic drug

✍ Scribed by Makoto Kuramoto; Koji Hayashi; Yasuyuki Fujitani; Kohji Yamaguchi; Tomoko Tsuji; Kaoru Yamada; Yasuharu Ijuin; Daisuke Uemura


Book ID
104257592
Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
217 KB
Volume
38
Category
Article
ISSN
0040-4039

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✦ Synopsis


The absolute configuration of norzoanthamine (1) was determined to be 2R, 4S, 6S, 9S, 10R, 12S, 13R, 18S, 21S, and 22S based on tH NMR spectral data of the MTPA esters of norzoanthamine derivatives. The possible biogenesis of zoanthamines is also proposed.


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