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Absolute configuration of C-1027 chromophore

✍ Scribed by Kyo-ichiro Iida; Sumiko Fukuda; Toshiyuki Tanaka; Masahiro Hirama; Seiichi Imajo; Masaji Ishiguro; Ken-ichiro Yoshida; Toshio Otani


Publisher
Elsevier Science
Year
1996
Tongue
French
Weight
210 KB
Volume
37
Category
Article
ISSN
0040-4039

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Construction of the highly unsaturated macrolactone of C-1027 chromophore (1) was investigated. Coupling of three fragments (2, 3, 4) led to the seco-acids in a concise manner. The protecting groups on the seco-acids influenced the yield of macrolactonization, and efficient conversion from acetonide

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