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Absence of α-synuclein affects dopamine metabolism and synaptic markers in the striatum of aging mice

✍ Scribed by Abdelmojib Al-Wandi; Natalia Ninkina; Steven Millership; Sally J.M. Williamson; Paul A. Jones; Vladimir L. Buchman


Book ID
116781436
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
671 KB
Volume
31
Category
Article
ISSN
0197-4580

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## Abstract Overexpression or mutation of α‐synuclein (α‐Syn), a protein associated with presynaptic vesicles, causes familial forms of Parkinson's disease in humans and is also associated with sporadic forms of the disease. We used in vivo microdialysis, tissue content analysis, behavioral assessm