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Absence of preproenkephalin increases the threshold for T cell activation

✍ Scribed by Sarah Hook; Mali Camberis; Melanie Prout; Graham Le Gros

Book ID
114137955
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
280 KB
Volume
140
Category
Article
ISSN
0165-5728

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## Abstract T cell (TC) activation requires the coordinated signaling of the T cell receptor (TCR) and coreceptor molecules, allowing TCs to respond to lower degrees of TCR occupancy. Coreceptor molecules set the threshold for TC activation by controlling different regulatory signaling loops. The C