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Absence of PPP2R1A mutations in Wilms tumor

✍ Scribed by Ruteshouser, E Cristy; Ashworth, Linda K; Huff, Vicki


Book ID
110064591
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
119 KB
Volume
20
Category
Article
ISSN
0950-9232

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## Abstract The Wilms' tumor 1 gene, __WT1__, encodes a zinc‐finger protein that is implicated in the development of Wilms' tumor. Mutant or aberrantly expressed WT1 isoforms have also been described in desmoplastic small round cell tumor, acute leukemias, mesothelioma, breast tumors and melanoma.