Pharmacokinetic interaction between dilt
โ
Joseph Ben David; Meir Bialer
๐
Article
๐
1989
๐
John Wiley and Sons
๐
English
โ 312 KB
๐ 2 views
The pharmacokinetic interaction between diltiazem and amiodarone was investigated in dogs. In the presence of amiodarone, diltiazem's AUC values were sigmfkantly increased and its total body clearance and volume of distribution at steady-state significantly decreased. This study indicates that cardi