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Absence of interaction between furosemide and mitomycin C

✍ Scribed by J. Verweij; S. Kerpel-Fronius; M. Stuurman; J. Vries; H. M. Pinedo

Publisher: Springer
Year: 1987
Tongue: English
Weight: 196 KB
Volume: 19
Category: Article
ISSN: 0344-5704
DOI: 10.1007/bf00296263

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✦ Synopsis

The possible interaction between furosemide and mitomycin C (MMC) was studied in five patients. The pharmacokinetics of MMC were studied using an HPLC assay. Furosemide was administered prior to, or 120 min after MMC. Furosemide did not change the pharmacokinetics of MMC, nor did it change the amount of MMC excreted in the urine. There appears to be no interaction between the two drugs.

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