## BACKGROUND. Human papillomavirus (HPV) infection represents the most important risk factor for cervical carcinoma. Levels of expression of E6 and E7 transforming oncoproteins of high risk HPV genotypes (i.e., HPV-16 and HPV-18) have been linked specifically to the mitotic activity of cervical c
Absence of Human Papillomavirus E6–E7 Transforming Genes from HPV 16 and 18 in Malignant Ovarian Carcinoma
✍ Scribed by Timothy R. Chen; Philip J. Chan; Ibrahim M. Seraj; Alan King
- Book ID
- 112247591
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 32 KB
- Volume
- 72
- Category
- Article
- ISSN
- 0090-8258
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## Abstract Human papillomavirus (HPV) infection is associated with cervical cancer. The E2 and E1 papillomavirus proteins are expressed at the early stage of infection and regulate DNA replication. The E2 protein activates and represses transcription from different HPVs promoters. At some stage wh
Certain human papillomaviruses (HPV), mainly types 16 and 18, have been widely recognized as an essential etiologic factor for the development of carcinoma of the uterine cervix. The early HPV proteins E6 and E7 are consistently expressed in the tumor cells, and cervical-carcinoma patients can devel