Absence of Hepatitis B Resistance Mutants Before Advent of Oral Antiviral Therapy
โ Scribed by Moehlen, Martin W.
- Book ID
- 123013123
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 76 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1542-3565
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The aim of this review is to summarize the safety profile of the five approved oral nucleoside analogs used to treat chronic hepatitis B virus (HBV) infection, focusing on both the class adverse effects and those that have been reported with individual agents, as well as their safety in pregnancy. A
Hepatitis B virus (HBV) mutants resistant to treatment with nucleoside or nucleotide analogs and those with the ability to escape from HBV-neutralizing antibody have the potential to infect HBV-vaccinated individuals. To address this potential serious public health challenge, we tested the efficacy