Type I diabetes has resisted direct genetic analysis in humans but two excellent models of disease in rodents provide a more readily manipulated alternative for study. These rodent models are being used successfully to localize the genes that are involved in disease pathogenesis in preparation for p
Absence of citrulline-specific autoantibodies in animal models of autoimmunity
✍ Scribed by Erik R. Vossenaar; Martinus A. M. van Boekel; Walther J. van Venrooij; Marcos López-Hoyoz; Jesús Merino; Ramón Merino; Leo A. B. Joosten
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 53 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0004-3591
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Abbreviations IDDM insulin-dependent diabetes mellitus IFN-γ γ interferon γ RA rheumatoid arthritis SE shared epitope TNF-α α tumor necrosis factor α
Evidence for a restricted idiotypic and epitopic specificity of anti-thyroglobulin autoantibodies in patients with autoimmune thyroiditis\* Anti-thyroglobulin (TG) autoantibodies from patients with autoimmune thyroiditis express a cross-reactive a idiotype (Id) termed T44 which is not expressed by I