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Absence of chromosome breakage in patients with retinoblastoma

✍ Scribed by Louise A. Knight; H. Allen Gardner; Brenda L. Gallie

Book ID
104700331
Publisher
Springer
Year
1979
Tongue
English
Weight
261 KB
Volume
51
Category
Article
ISSN
0340-6717

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✦ Synopsis

Mixed lymphocyte cultures were employed to assess the degree of spontaneous chromosome fragility in patients with retinoblastoma. There was no difference between the patients and their controls. If chromosome instability plays a role in the inherited tumour, more sensitive methods need be employed to elucidate it.

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