Absence of Borrelia burgdorferi in patients with localized scleroderma (morphea)
✍ Scribed by Weixin Fan; Craig L Leonardi; Neal S Penneys
- Book ID
- 116111723
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 368 KB
- Volume
- 33
- Category
- Article
- ISSN
- 1097-6787
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## Abstract **Background** Morphea and lichen sclerosus et atrophicus (LSA) are sclerotic skin lesions of unknown etiology involving connective tissue. The hypothesis of a borrelial origin of morphea and LSA is currently controversial. **Methods** Immunoglobulin G (IgG) immunoblot serologies again
Spirochetal organisms were sought in 18 skin and 4 synovial membrane specimens obtained by biopsy from 22 Lyme disease patients. The presence of spirochetes in body tissues was histologically demonstrated in one patient with lymphadenosis benigna cutis, one patient with acrodermatitis chronica atrop