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Absence of Bcl-2 and Fas/CD95/APO-1 predicts the response to immunotherapy in metastatic renal cell carcinoma

โœ Scribed by Maruyama, R; Yamana, K; Itoi, T; Hara, N; Bilim, V; Nishiyama, T; Takahashi, K; Tomita, Y


Book ID
109998944
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
189 KB
Volume
95
Category
Article
ISSN
0007-0920

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Expression of the CD95 (APO-1/Fas) ligand (CD95L) in activated T cells is a major cause of activation-induced T cell apoptosis. The transcription factors NF-AT and Egr-3 (a member of the immediate-early transcription factors involved in cellular growth and differentiation) have been implicated in ac