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Absence of association between a mitochondrial DNA mutation at nucleotide position 3243 and schizophrenia in Japanese

โœ Scribed by M. Odawara; Tadao Arinami; Yoichi Tachi; Hideo Hamaguchi; Michio Toru; Kamejiro Yamashita


Publisher
Springer
Year
1998
Tongue
English
Weight
42 KB
Volume
102
Category
Article
ISSN
0340-6717

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We have developed an improved allele-specific polymerase chain reaction (AS-PCR) procedure that can selectively amplify mutant DNA sequences (which differ from the normal sequences by a single base pair) in the presence of large excess of normal sequences. We applied this procedure to quantification