The mutation spectrum of the APC gene in
โ
Marina De Rosa; Maria I. Scarano; Luigi Panariello; Gemma Morelli; Gabriele Rieg
๐
Article
๐
2003
๐
John Wiley and Sons
๐
English
โ 43 KB
๐ 1 views
Paalman Familial adenomatous polyposis (FAP), an autosomal dominantly inherited condition accounting for about 1% of all colorectal cancers, results from mutations in the adenomatous polyposis coli (APC) tumor suppressor gene. The clinical spectrum and severity of FAP varies greatly with the mutatio