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Absence of a radiation-induced adaptive response of lymphocytes in Down's syndrome

โœ Scribed by E. K. Khandogina; G. R. Mutovin; S. V. Zvereva; D. O. Zverev; E. V. Neudakhin; B. A. Arkhipov; A. P. Akif'ev

Book ID
104967939
Publisher
Springer US
Year
1991
Tongue
English
Weight
213 KB
Volume
112
Category
Article
ISSN
0007-4888

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Down syndrome (DS) individuals are known to be predisposed to develop leukemia and their lymphocytes are highly sensitive to the induction of chromosome aberrations by X-rays. A study was conducted to identify the chromosome breakpoints and to evaluate whether site specificity for chromosome breakag