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Abrin and Ricin: New Anti-tumour Substances

✍ Scribed by LIN, JUNG-YAW; TSERNG, KOU-YI; CHEN, CHI-CHING; LIN, LEE-TZU; TUNG, TA-CHENG

Book ID
109674398
Publisher
Nature Publishing Group
Year
1970
Tongue
English
Weight
197 KB
Volume
227
Category
Article
ISSN
0028-0836

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## Abstract Twenty‐three monoclonal antibodies (MAbs) against the IL‐2 receptor α‐chain (CD25) were evaluated as ricin A‐chain immunotoxins for the treatment of Hodgkin's disease. Primary screening used an indirect assay in which the cells were treated with the test antibody followed by a Fab immun