𝔖 Bobbio Scriptorium
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ABP50: An actin-binding elongation factor 1α from Dictyostelium discoideum

✍ Scribed by Brian T. Edmonds


Book ID
102880274
Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
530 KB
Volume
52
Category
Article
ISSN
0730-2312

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✦ Synopsis


ABP50 is a polypeptide elongation factor la from Dictyosteliurn that is associated with the actin cytoskeleton. Upon chemotactic stimulation, ABP50 undergoes a dramatic cytoplasmic redistribution into newly formed surface projections and in vitro binds to and bundles actin filaments. Many questions are raised by this interaction pertaining to the spatiotemporal regulation of protein synthesis and cytoskeletal organization by extracellular signals.


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