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About the reaction of β-dimethylamino-α,β-enones with active methylene nitriles

✍ Scribed by Fathy M. Abdelrazek; Akram N. Elsayed

Publisher: Journal of Heterocyclic Chemistry
Year: 2009
Tongue: English
Weight: 101 KB
Volume: 46
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.181

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✦ Synopsis

Abstract

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The reaction of 3‐dimethylamino‐1‐arylpropenone derivatives with active methylene nitriles was reinvestigated and a plausible mechanism to account for the results is suggested. X‐ray crystallographic study supported the suggested mechanism. Based on these findings, the reaction of 3‐acetylamino‐4‐dimethylaminobut‐3‐en‐2‐one with malononitrile was also reinvestigated and the correct structures verified. J. Heterocyclic Chem., (2009).

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