A model for topological coding of proteins is proposed. The model is based on the capacity of hydrogen bonds (property of connectivity) to "x conformations of protein molecules. The protein chain is modeled by an n-arc graph with the following elements: vertices ( -carbon atoms), structural edges (p
About a Symmetry of the Genetic Code
β Scribed by A.J. Koch; J. Lehmann
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 176 KB
- Volume
- 189
- Category
- Article
- ISSN
- 0022-5193
No coin nor oath required. For personal study only.
β¦ Synopsis
Considering the three codonic positions as independent, it is possible to explain the grouping of the 64 trinucleotides (without AAA, TTT, CCC and GGG) into three equal sets T0, T1 and T2 according to their preferable reading frame (0, 1 or 2) in coding sequences. Supposing that the two complementarity strands of DNA are coding, it is demonstrated that the complementary of a codon is classified in to the same set, which has been observed statistically (with a few exceptions) in the coding sequences by Arquès & Michel [(1996) J. theor. Biol. 182, 45-58] and Arquès et al. [(1997) J. theor. Biol. 185, 241-253]. Finally, the circular property of the code pointed out by these authors is demonstrated, and a direct consequence to biological considerations of these properties is discussed.
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