About a Practical Synthesis of Ambrox® (II) from Sclareol (I): A New Preparation of a Ketone Key Intermediate (III) and a Close Look at Its Baeyer—Villiger Oxidation.

About a Practical Synthesis of Ambrox® f

About a Practical Synthesis of Ambrox® from Sclareol: a New Preparation of a Ketone Key Intermediate and a Close Look at its Baeyer–Villiger Oxidation

✍ Jean Moulines; Jean-Paul Bats; Anne-Marie Lamidey; Nicole Da Silva 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 German ⚖ 230 KB

## Abstract The latest route to __Ambrox__^®^ (**1**) starting from sclareol (**2**) proceeds through an oxy ketone **4** (__Scheme 1__). A new practical synthesis of the key intermediate **4** is described; it is equivalent to a partial oxidative degradation of sclareol (**2**) with peracetic and