Abnormalities of chromosome 7 in human malignant melanoma. Relation with tumourigenicity in nude mice and arginine metabolism

RAS, FLT3, and TP53 mutations in therapy

RAS, FLT3, and TP53 mutations in therapy-related myeloid malignancies with abnormalities of chromosomes 5 and 7

✍ Lucy E. Side; Nicole P. Curtiss; Kathryn Teel; Christian Kratz; Pauline W. Wang; 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 114 KB

## Abstract Oncogenic mutations in the __KRAS2__, __NRAS__, or __FLT3__ gene are detected in more than 50% of patients with de novo acute myeloid leukemia (AML). __RAS__ mutations are also prevalent in de novo myelodysplastic syndrome (MDS), especially chronic myelomonocytic leukemia and juvenile m